{"id":8242,"date":"2020-11-23T06:55:07","date_gmt":"2020-11-23T06:55:07","guid":{"rendered":"https:\/\/labsites.rochester.edu\/gsharma\/?page_id=8242"},"modified":"2020-11-29T00:08:55","modified_gmt":"2020-11-29T00:08:55","slug":"deep-retinal-vessel-segmentation-for-ultra-widefield-fundus-photography","status":"publish","type":"page","link":"https:\/\/labsites.rochester.edu\/gsharma\/research\/computer-vision\/deep-retinal-vessel-segmentation-for-ultra-widefield-fundus-photography\/","title":{"rendered":"Deep Retinal Vessel Segmentation For Ultra-Widefield Fundus Photography"},"content":{"rendered":"<p style=\"text-align: left;\">L. Ding, A. E. Kuriyan, R. S. Ramchandran, C. C. Wykoff, and G. Sharma, \u201cWeakly-supervised vessel detection in ultra-widefield fundus photography via iterative multi-modal registration and learning,\u201d IEEE Trans. Medical Imaging, accepted for publication, to appear.<\/p>\n<p style=\"text-align: center;\"><a href=\"http:\/\/www.ece.rochester.edu\/~gsharma\/papers\/Ding_IterVDRegUWFFP_TMI2020.pdf\" rel=\"nofollow\">[Paper]<\/a>\u00a0<a href=\"http:\/\/www.ece.rochester.edu\/~gsharma\/papers\/Suppl_Ding_IterVDRegUWFFP_TMI2020.pdf\" rel=\"nofollow\">[Supplementary]<\/a>\u00a0<a href=\"https:\/\/doi.org\/10.21227\/ctgj-1367\" rel=\"nofollow\">[Dataset]<\/a> [<a href=\"https:\/\/github.com\/ShamaLabUR\/DeepVesselSeg4FP\">GitHub<\/a>]\u00a0<a href=\"https:\/\/doi.org\/10.24433\/CO.5712234.v1\" rel=\"nofollow\">[Code Ocean capsule]<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8262\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview.png\" alt=\"\" width=\"700\" height=\"231\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview.png 1580w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview-300x99.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview-1024x338.png 1024w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview-768x254.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview-1536x507.png 1536w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/UWFFP_VD_Overview-624x206.png 624w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/p>\n<p>In this work, we focus on retinal vessel segmentation in ultra-widefield (UWF) fundus photography (FP), a retinal imaging modality that has received limited attention in prior works. UWF FP is noninvasive, only involves the capture of the retinal images under low-power illumination, and provides a wide field-of-view. We propose an annotation-efficient framework for vessel segmentation in UWF FP that eliminates the requirement of manually<br \/>\nlabeled datasets for supervised learning.<\/p>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Contributions<\/strong><\/span>\n<ul>\n<li>We present a novel iterative framework for vessel detection in UWF FP using DNNs. We rely on datasets that include concurrently captured UWF fluorescein angiography (FA) images, for which effective deep learning approaches for vessel detection have recently become <a href=\"https:\/\/labsites.rochester.edu\/gsharma\/research\/computer-vision\/deep-retinal-vessel-segmentation-for-fluorescein-angiography-fa-retinal-images\/\">available<\/a> allowing for accurate vessel detection. The proposed framework<br \/>\nthen jointly addresses precise registration between the vessel images for the modalities and vessel segmentation in UWF FP.<\/li>\n<li>We construct a new ground truth labeled dataset, <a href=\"#PRIME-FP20\">PRIME-FP20<\/a>, to evaluate retinal vessel detection in UWF FP and to facilitate further work on this problem.<\/li>\n<li>The proposed framework provides a method for accurate vessel detection in UWF FP imagery, a modality that has received limited attention in prior works. The proposed approach significantly outperforms existing methods on the PRIME-FP20 dataset and, on narrow-field FP datasets, achieves performance comparable with state-of-the-art methods designed specifically for narrow-fiel FP. [<a href=\"https:\/\/github.com\/ShamaLabUR\/DeepVesselSeg4FP\">GitHub<\/a>] [<a href=\"https:\/\/codeocean.com\/capsule\/3563384\/tree\/v1\">Code Ocean capsule<\/a>]<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li><span style=\"font-family: arial,helvetica,sans-serif; font-size: 14pt;\"><strong><a id=\"PRIME-FP20\"><\/a>PRIME-FP20: Ultra-Widefield Fundus Photography Vessel Segmentation Dataset<\/strong><\/span>\n<ul>\n<li>The PRIME-FP20 dataset contains 15 high-resolution ultra-widefield (UWF) <strong>fundus photography<\/strong> (FP), the corresponding labeled <strong>binary vessel maps<\/strong>, and the corresponding <strong>binary masks<\/strong> for the valid data region for the images. For each UWF FP image, a concurrently captured ultra-widefield <strong>fluorescein angiography<\/strong> (FA) is also included.<\/li>\n<li>UWF FP images are acquired using the Optos 200Tx camera (Optos plc, Dunfermline, United Kingdom). The system uses a scanning ophthamoscope with a low power laser<br \/>\nto capture dual red and green channel UWF FP images and a single channel FA image.<\/li>\n<li>All images have the same resolution of 4000&#215;4000 pixels and are stored as 8-bit TIFF format with lossless LZW compression.<\/li>\n<li>You can download the dataset from <a href=\"https:\/\/doi.org\/10.21227\/ctgj-1367\">IEEE DataPort<\/a>. This is an open-access dataset available to all IEEE users (IEEE Accounts are FREE).<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<div id=\"attachment_8182\" style=\"width: 635px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8182\" class=\"wp-image-8182 size-large\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20-1024x498.png\" alt=\"\" width=\"625\" height=\"304\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20-1024x498.png 1024w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20-300x146.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20-768x374.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20-624x304.png 624w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/cover_figure_PRIME-FP20.png 1251w\" sizes=\"auto, (max-width: 625px) 100vw, 625px\" \/><p id=\"caption-attachment-8182\" class=\"wp-caption-text\">Example of labeled ground truth vessel map from the PRIME-FP20 dataset.<\/p><\/div>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Sample Results<\/strong><\/span><\/li>\n<li><span style=\"font-size: 12pt;\"><strong>Quantitative results on PRIME-FP20 dataset<\/strong><\/span><\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8412\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20.png\" alt=\"\" width=\"700\" height=\"257\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20.png 1249w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20-300x110.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20-1024x375.png 1024w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20-768x282.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/quant_prime_fp20-624x229.png 624w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/p>\n<ul>\n<li><span style=\"font-size: 12pt;\"><strong>Visual results on RECOVERY-FA19 dataset<\/strong><\/span><\/li>\n<\/ul>\n<div id=\"attachment_8432\" style=\"width: 710px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8432\" class=\"wp-image-8432\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20.png\" alt=\"\" width=\"700\" height=\"485\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20.png 1184w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20-300x208.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20-1024x709.png 1024w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20-768x532.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2020\/11\/visual_prime_fp20-624x432.png 624w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><p id=\"caption-attachment-8432\" class=\"wp-caption-text\">Visual comparison of results obtained with different algorithms for images from the PRIME-FP20 dataset. For each full image, two contrast-enhanced enlarged views of the selected regions (shown by cyan rectangles) are also included.<\/p><\/div>\n<p><span style=\"font-size: 14pt; font-family: arial,helvetica,sans-serif;\"><strong>Publication<\/strong><\/span><\/p>\n<p>L. Ding, A. E. Kuriyan, R. S. Ramchandran, C. C. Wykoff, and G. Sharma, \u201cWeakly-supervised vessel detection in ultra-widefield fundus photography via iterative multi-modal registration and learning,\u201d IEEE Trans. Medical Imaging, accepted for publication, to appear.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>L. Ding, A. E. Kuriyan, R. S. Ramchandran, C. C. Wykoff, and G. Sharma, \u201cWeakly-supervised vessel detection in ultra-widefield fundus photography via iterative multi-modal registration and learning,\u201d IEEE Trans. Medical Imaging, accepted for publication, to appear. [Paper]\u00a0[Supplementary]\u00a0[Dataset] [GitHub]\u00a0[Code Ocean capsule] In this work, we focus on retinal vessel segmentation in ultra-widefield (UWF) fundus photography (FP), [&hellip;]<\/p>\n","protected":false},"author":32,"featured_media":0,"parent":882,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width.php","meta":{"footnotes":""},"class_list":["post-8242","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/Paivks-28W","_links":{"self":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/8242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/comments?post=8242"}],"version-history":[{"count":18,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/8242\/revisions"}],"predecessor-version":[{"id":8722,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/8242\/revisions\/8722"}],"up":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/882"}],"wp:attachment":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/media?parent=8242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}