{"id":1732,"date":"2017-05-12T16:03:49","date_gmt":"2017-05-12T16:03:49","guid":{"rendered":"https:\/\/labsites.rochester.edu\/gsharma\/?page_id=1732"},"modified":"2018-05-02T22:18:29","modified_gmt":"2018-05-02T22:18:29","slug":"medbioinformatics","status":"publish","type":"page","link":"https:\/\/labsites.rochester.edu\/gsharma\/research\/medbioinformatics\/","title":{"rendered":"Medical and Bio Informatics"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1842 alignleft\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/BioInfo-300x186.png\" alt=\"\" width=\"300\" height=\"186\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/BioInfo-300x186.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/BioInfo.png 400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p><span style=\"font-size: 14pt;\"><strong>RNA Structure Estimation from Multiple Homologs<span id=\"sample-permalink\" style=\"font-size: 10pt;\">[<a href=\"https:\/\/labsites.rochester.edu\/gsharma\/research\/medbioinformatics\/rnastructestim\/\">project page<\/a>]<\/span><\/strong><\/span><\/p>\n<p>Nature encodes the functional structure of a (noncoding) RNA molecule as multiple alternative homologous sequences in different organisms. In our work, we seek to decode this common structure by exploiting this comparative information across the multiple homologs in combination with thermodynamic models for predicting secondary structure.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-4112 alignleft\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result-300x225.png\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result-300x225.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result-768x576.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result-1024x768.png 1024w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result-624x468.png 624w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/08\/synthetic_wisem_result.png 1600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><span style=\"font-size: 14pt;\"><strong>Data Analytics for Large Scale Flow Cytometry Data<span id=\"sample-permalink\" style=\"font-size: 10pt;\">[<a href=\"http:\/\/www.ece.rochester.edu\/projects\/siplab\/Software\/SWIFT.html\">project page<\/a>]<\/span><\/strong><\/span><\/p>\n<p>Flow cytometry (FC) is a powerful technology for rapid measurements of multiple attributes at the individual cell level for populations with millions of cells. In our work, we focus on automated analysis of the large scale datasets generated by flow-cytometry.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-4292 alignleft\" src=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/pdhdforwebv3-300x202.png\" alt=\"\" width=\"300\" height=\"202\" srcset=\"https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/pdhdforwebv3-300x202.png 300w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/pdhdforwebv3-768x518.png 768w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/pdhdforwebv3-624x421.png 624w, https:\/\/labsites.rochester.edu\/gsharma\/wp-content\/uploads\/2017\/05\/pdhdforwebv3.png 848w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><strong style=\"font-size: 1rem;\"><span style=\"font-size: 14pt;\">Sensor Data Analytics for Parkinson&#8217;s and Huntington&#8217;s Diseases<\/span>\u00a0<\/strong><\/p>\n<p>Parkinson&#8217;s and Huntington&#8217;s diseases are progressive neurological conditions that cause movement disorders in affected individuals. In our work we utilize multiple body-affixed sensors to obtain long duration three dimensional accelerometer data. We use machine learning techniques on the data for tracking progression of disease, medication efficacy, enabling personalized medicine and early prognosis.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 14pt;\"><strong>Selected Publications<\/strong><\/span><\/p>\n<div class=\"teachpress_pub_list\"><form name=\"tppublistform\" method=\"get\"><a name=\"tppubs\" id=\"tppubs\"><\/a><\/form><div class=\"teachpress_message_error\"><p>Sorry, no publications matched your criteria.<\/p><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>RNA Structure Estimation from Multiple Homologs[project page] Nature encodes the functional structure of a (noncoding) RNA molecule as multiple alternative homologous sequences in different organisms. In our work, we seek to decode this common structure by exploiting this comparative information across the multiple homologs in combination with thermodynamic models for predicting secondary structure. &nbsp; Data [&hellip;]<\/p>\n","protected":false},"author":32,"featured_media":0,"parent":1592,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width.php","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-1732","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/Paivks-rW","_links":{"self":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/1732","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/comments?post=1732"}],"version-history":[{"count":17,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/1732\/revisions"}],"predecessor-version":[{"id":4612,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/1732\/revisions\/4612"}],"up":[{"embeddable":true,"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/pages\/1592"}],"wp:attachment":[{"href":"https:\/\/labsites.rochester.edu\/gsharma\/wp-json\/wp\/v2\/media?parent=1732"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}